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Investigating the long-term impact of a programme of mindfulness combined with exercise delivered online (MOVE) on individuals living with chronic pain-an exploratory one-year follow-up of a feasibility randomised control trial

Authors: Deegan, O. and Yoshitani, M. and Fullen, B. and Gordon, M. and McDonagh, O. and Sheerin, O. and Murphy, J. and Oyebode, O. and Segurado, R. and Hearty, C. and Casey, M. B. and Doody, C.

Year: 2025 Journal: PLoS One Vol/Issue: Vol. 20, No. 9 Pages: e0323508

Study Characteristics

Lifestyle Pillars
Physical ActivityStress Management
Study Design
RCT

Abstract

Background

Online pain management programmes have evidence as effective interventions for individuals with chronic pain. This study was a one-year exploratory follow-up of a parallel group feasibility randomised controlled trial (RCT) investigating the effectiveness of participating in an online pain management programme that combined Mindfulness-Based Stress Reduction (MBSR) and exercise delivered online for individuals living with chronic pain (MOVE).

Methods

Ninety-six individuals with chronic pain participated in an eight-week feasibility RCT comparing MBSR and exercise to an online self-management guide. Fourteen patient reported outcome measures (PROMS) were collected at baseline, post-intervention, three months post-intervention and at a one-year follow-up. Analysis of changes in PROMs between baseline and one-year follow-up in the current study were analysed using Student's t-tests, and in addition, data were analysed using linear mixed models, examining effect sizes.

Results

Forty-eight participants completed PROMs at a one-year follow-up. Small between group differences were observed in depression and the mental health component of the health-related quality of life score, in favour of the combined MBSR and exercise group. A further nine PROMS showed improvements in favour of the self-management group (SM). In the MOVE group, one-year follow-up scores demonstrated trends towards improvement compared to baseline scores for 10/14 PROMs. In the SM group positive changes were found in 13/14 PROMs. At one-year follow-up, results from the Patients Global Impression of Change Scale, demonstrated that 63.3% of participants in the combined mindfulness and exercise group, and 44.4% of participants in the self-management group reported improvement with a noticeable change.

Conclusions

The results of this long-term exploratory study suggest no significant difference between groups for the investigated PROMs at one-year follow-up. A fully powered RCT examining the effectiveness of MBSR combined with exercise delivered in a live synchronous online format is warranted, to explore the factors to optimise long-term outcomes for people living with chronic pain.