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Improving cardiometabolic risk factors in Aboriginal and Torres Strait Islander people in northeast Arnhem Land: single arm trial of a co-designed dietary and lifestyle program

Authors: Dissanayake, H. U. and Gurruwiwi, G. and Dhurrkay, J. and Tynan, J. C. and Braat, S. and Harrap, B. and Trudgen, T. and Hanieh, S. and Clark, B. and Spencer, M. and Christie, M. and Tonkin, E. and Armstrong, E. and Harrison, L. C. and Wentworth, J. M. and Brimblecombe, J. K. and Biggs, B. A.

Year: 2025 Journal: Med J Aust Vol/Issue: Vol. 222, No. 4 Pages: 183-190

Study Characteristics

Lifestyle Pillars
NutritionPhysical Activity
Study Design
Single-arm intervention

Abstract

Objective

To evaluate the impact of a 4-month dietary and lifestyle program co-designed and led by Aboriginal and Torres Strait Islander people on weight and metabolic markers, diet, and physical activity in overweight and obese adults in a remote Indigenous community.

Study Design

Single arm, pre-post intervention study. SETTING, PARTICIPANTS: Adult residents (18-65 years) of a remote Northern Territory community with body mass index (BMI) values of at least 25 kg/m(2) or waist circumferences exceeding 94 cm (men) or 80 cm (women).

Intervention

Hope for Health, a culturally sensitive 4-month program supporting self-managed health improvement based on dietary and lifestyle change, 1 August to 30 November 2022.

Main Outcome Measures

Weight loss of at least 5%; changes in BMI, waist circumference, other metabolic markers (blood pressure, biomarkers of metabolic health and inflammation), diet, and physical activity; participant perceptions of the program.

Results

We assessed outcomes for 55 participants who completed weight assessments at both baseline and program end (mean age, 42.5 years [standard deviation, 10.1 years]; 36 women [65%]). Forty participants lost and 15 gained weight; overall mean weight loss was 1.5 kg (95% confidence interval [CI], 0.5-2.4 kg), and ten participants (18%; 95% CI, 9-31%) achieved at least 5% weight reduction. The mean change in BMI (53 participants) was -0.60 kg/m(2) (95% CI, -0.93 to -0.27 kg/m(2)), in waist circumference (53 participants) -3.2 cm (95% CI, -4.7 to -1.7 cm), and in low-density lipoprotein cholesterol level (37 participants) -0.28 mmol/L (95% CI, -0.47 to -0.08 mmol/L); the relative decline in the HbA(1c) level geometric mean (50 participants) was 11% (95% CI, 6-15%). The intake of breads and cereals (median change, -1.5 [95% CI, -2.0 to -1.0] serves/day) and sugar-sweetened beverages (-0.6 [95% CI, -1.4 to -0.1] serves/day) declined; the amount of moderate and vigorous physical activity increased by a median of 103 min/day (95% CI, 74-136 min/day; 19 participants). The program focus on integrating healthy bodies and networks of kin, healthy governance, vibrant language and ceremony, and a healthy environment were seen as central to its value and benefit.

Conclusions

Community appreciation of the program and the improvements in cardiometabolic risk factors are encouraging, providing an example of a culturally sensitive, co-designed initiative led by Indigenous people for reducing the prevalence of chronic disease in remote areas.

Trial Registration

Australian New Zealand Clinical Trials Registry (ACTRN12622000174785; prospective: 2 February 2022).