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Global prevalence of female sexual dysfunction based on physical activity: a systematic review and meta-analysis

Authors: Salari, N. and Hasheminezhad, R. and Hosseinian-Far, A. and Mohammadi, M.

Year: 2025 Journal: BMC Womens Health Vol/Issue: Vol. 25, No. 1 Pages: 200

Study Characteristics

Lifestyle Pillars
Physical Activity
Study Design
Meta-analysis/Sys Review

Abstract

Background

There is a strong connection between physical activity and major non-communicable diseases. Women's sexual health is a vital aspect of life at any age; however, it is influenced by many factors. The aim of this study is to investigate the global prevalence of female sexual dysfunction based on physical activity through a systematic review and meta-analysis.

Methods

In this study, electronic repositories including PubMed, Google scholar, Scopus, Web of Science, Embase, and ScienceDirect were systematically searched using specified keywords, without a lower time limit, up until March 2025. A random effects model was employed to perform the meta-analysis. The heterogeneity of the studies was assessed using the I(2) index. Data analysis was conducted within the Comprehensive Meta-Analysis (CMA) software (version 2).

Results

In the review of 7 studies with a sample size of 1,776 participants, the pooled prevalence of female sexual dysfunction with high physical activity was estimated to be 47% (95% CI: 28.8-65.9). Also, in the review of 6 studies with a sample size of 2,094 participants, the pooled prevalence of female sexual dysfunction among those with low physical activity or a sedentary lifestyle was found to be 64.6% (95% CI: 44.5-80.6).

Conclusion

In this meta-analysis, the pooled prevalence of sexual dysfunction among inactive women was reported to be higher and more significant than that of physically active women. Thus, it is necessary for health policymakers to further promote the importance of physical activity to prevent and reduce female sexual dysfunction.